Human AHSG / Alpha-2-HS-glycoprotein ELISA Kit; for serum; plasma and cell culture supernatants

Application

For research use only. Not for use in diagnostic procedures.Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Biochem/physiol Actions

α 2-HS glycoprotein (AHSG), also referred to as fetuin-A, is a major serum protein component that exerts various calcium-dependent physiological activities and can mediate growth signaling in certain tumor cells. It can also act as a natural antagonist against specific TGF-β (transforming growth factor β) and BMP (bone morphogenetic protein) signaling proteins. High levels of fetuin-A in the serum is associated with mild osteogenesis imperfecta. On the other hand, reduced levels are seen in Paget′s disease. It is predicted as a potential biomarker for the early diagnosis of hypopharyngeal squamous cell carcinoma.

General description

This ELISA antibody pair detects human Alpha-2-HS-glycoprotein.

Other Notes

A sample Certificate of Analysis is available for this product.Please type the word sample in the text box provided for lot number.